Structure of PDB 7xkd Chain R

Receptor sequence
>7xkdR (length=261) Species: 9606 (Homo sapiens) [Search protein sequence]
QMMALTFITYIGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALL
LLNLIFLLDSWIALYNTRGFCIAVAVFLHYFLLVSFTWMGLEAFHMYLAL
VKVFNTYIRKYILKFCIVGWGIPAVVVSIVLTISPDNYGIGNGTPDDFCW
INSNVVFYITVVGYFCVIFLLNVSMFIVVLVQLCRIKKKKQLGAQRKTSI
QDLRSIAGLTFLLGITWGFAFFAWGVNVTFMYLFAIFNTLQGFFIFIFYC
AAKENVRKQWR
3D structure
PDB7xkd Structures of the ADGRG2-G s complex in apo and ligand-bound forms.
ChainR
Resolution2.4 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 AND R T765 M853 F856 T144 M231 F234
Gene Ontology
Molecular Function
GO:0004888 transmembrane signaling receptor activity
GO:0004930 G protein-coupled receptor activity
Biological Process
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G protein-coupled receptor signaling pathway
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7xkd, PDBe:7xkd, PDBj:7xkd
PDBsum7xkd
PubMed35982227
UniProtQ8CJ12|AGRG2_MOUSE Adhesion G-protein coupled receptor G2 (Gene Name=Adgrg2)

[Back to BioLiP]