Structure of PDB 7wu5 Chain R

Receptor sequence
>7wu5R (length=286) Species: 9606 (Homo sapiens) [Search protein sequence]
ASFSILMSPFVPSTIFPVVKWITYVGLGISIGSLILCLIIEALFWKQIKK
SQTSHTRRICMVNIALSLLIADVWFIVGATVDTTVNPSGVCTAAVFFTHF
FYLSLFFWMLMLGILLAYRIILVFHHMAQHLMMAVGFCLGYGCPLIISVI
TIAVTQPSNTYKRKDVCWLNWSNGSKPLLAFVVPALAIVAVNFVVVLLVL
TKLWRPTVGERLSRDDKATIIRVGKSLLILTPLLGLTWGFGIGTIVDSQN
LAWHVIFALLNAFQGFFILCFGILLDSKLRQLLFNK
3D structure
PDB7wu5 Structural basis of tethered agonism of the adhesion GPCRs ADGRD1 and ADGRF1.
ChainR
Resolution3.0 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CLR R F759 F806 I808 F193 F240 I242
BS02 K6G R T622 I625 W674 M677 I680 I687 L688 M698 V701 G702 T56 I59 W108 M111 I114 I121 L122 M132 V135 G136
Gene Ontology
Molecular Function
GO:0004888 transmembrane signaling receptor activity
GO:0004930 G protein-coupled receptor activity
Biological Process
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G protein-coupled receptor signaling pathway
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7wu5, PDBe:7wu5, PDBj:7wu5
PDBsum7wu5
PubMed35418679
UniProtQ5T601|AGRF1_HUMAN Adhesion G-protein coupled receptor F1 (Gene Name=ADGRF1)

[Back to BioLiP]