Structure of PDB 7wu4 Chain R

Receptor sequence
>7wu4R (length=286) Species: 9606 (Homo sapiens) [Search protein sequence]
TSFSILMSPFVPSTIFPVVKWITYVGLGISIGSLILCLIIEALFWKQIKK
SQTSHTRRICMVNIALSLLIADVWFIVGATVDTTVNPSGVCTAAVFFTHF
FYLSLFFWMLMLGILLAYRIILVFHHMAQHLMMAVGFCLGYGCPLIISVI
TIAVTQPSNTYKRKDVCWLNWSNGSKPLLAFVVPALAIVAVNFVVVLLVL
TKLWRPTVGERLSRDDKATIIRVGKSLLILTPLLGLTWGFGIGTIVDSQN
LAWHVIFALLNAFQGFFILCFGILLDSKLRQLLFNK
3D structure
PDB7wu4 Structural basis of tethered agonism of the adhesion GPCRs ADGRD1 and ADGRF1.
ChainR
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CLR R F759 G805 F806 I808 F193 G239 F240 I242
BS02 K6G R C626 W674 M677 L681 Y684 M698 M699 G702 C60 W108 M111 L115 Y118 M132 M133 G136
Gene Ontology
Molecular Function
GO:0004888 transmembrane signaling receptor activity
GO:0004930 G protein-coupled receptor activity
Biological Process
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G protein-coupled receptor signaling pathway
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7wu4, PDBe:7wu4, PDBj:7wu4
PDBsum7wu4
PubMed35418679
UniProtQ5T601|AGRF1_HUMAN Adhesion G-protein coupled receptor F1 (Gene Name=ADGRF1)

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