Structure of PDB 7wu3 Chain R

Receptor sequence
>7wu3R (length=280) Species: 9606 (Homo sapiens) [Search protein sequence]
TSFSILMSPFVPSTIFPVVKWITYVGLGISIGSLILCLIIEALFWKQIKK
SQTSHTRRICMVNIALSLLIADVWFIVGATVSGVCTAAVFFTHFFYLSLF
FWMLMLGILLAYRIILVFHHMAQHLMMAVGFCLGYGCPLIISVITIAVTQ
PSNTYKRKDVCWLNWSNGSKPLLAFVVPALAIVAVNFVVVLLVLTKLWRP
TVGERLSRDDKATIIRVGKSLLILTPLLGLTWGFGIGTIVDSQNLAWHVI
FALLNAFQGFFILCFGILLDSKLRQLLFNK
3D structure
PDB7wu3 Structural basis of tethered agonism of the adhesion GPCRs ADGRD1 and ADGRF1.
ChainR
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 K6G R C626 M677 Y684 L688 M698 C60 M105 Y112 L116 M126
Gene Ontology
Molecular Function
GO:0004888 transmembrane signaling receptor activity
GO:0004930 G protein-coupled receptor activity
Biological Process
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G protein-coupled receptor signaling pathway
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7wu3, PDBe:7wu3, PDBj:7wu3
PDBsum7wu3
PubMed35418679
UniProtQ5T601|AGRF1_HUMAN Adhesion G-protein coupled receptor F1 (Gene Name=ADGRF1)

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