Structure of PDB 7vvo Chain R

Receptor sequence
>7vvoR (length=302) Species: 9606 (Homo sapiens) [Search protein sequence]
TKEEQIFLLHRAQAQCEKRLVVAVPCPDYIYDFNHKGHAYRRCDRNGSWE
LVPGHNRTWANYSECVKFLRLGMIYTVGYSVSLASLTVAVLILAYFRRLH
CTRNYIHMHLFLSFMLRAVSIFVKDAGCRVAVTFFLYFLATNYYWILVEG
LYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVSVRATLANGNKKW
IIQVPILASIVLNFILFINIVRVLATKLRETDTRQQYRKLLKSTLVLMPL
FGVHYIVFMATPYTEVHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWS
RW
3D structure
PDB7vvo Endogenous ligand recognition and structural transition of a human PTH receptor.
ChainR
Resolution4.1 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide R I237 F288 L289 L292 Q364 T427 E444 I121 F135 L136 L139 Q203 T261 E269
Gene Ontology
Molecular Function
GO:0004888 transmembrane signaling receptor activity
GO:0004930 G protein-coupled receptor activity
GO:0004991 parathyroid hormone receptor activity
Biological Process
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G protein-coupled receptor signaling pathway
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7vvo, PDBe:7vvo, PDBj:7vvo
PDBsum7vvo
PubMed35932760
UniProtQ03431|PTH1R_HUMAN Parathyroid hormone/parathyroid hormone-related peptide receptor (Gene Name=PTH1R)

[Back to BioLiP]