Structure of PDB 7t11 Chain R

Receptor sequence
>7t11R (length=285) Species: 9606 (Homo sapiens) [Search protein sequence]
NAVLTFIYFVVCIIGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELF
MLGLPFLAMQVALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYL
AVVHPIKSAKWRRPRTAKMITMAVWGVSLLVILPIMIYAGLRSNQWGRSS
CTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYLFIIIKVKSVRLLS
GSREKDRNLRKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPALKG
MFDFVVVLTYANSCANPILYAFLSDNFKKSFQNVL
3D structure
PDB7t11 Plasticity in ligand recognition at somatostatin receptors.
ChainR
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide R Q102 N186 W188 Y205 I209 F272 P286 F294 Q60 N144 W146 Y163 I167 F230 P244 F252
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0004994 somatostatin receptor activity
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
Cellular Component
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:7t11, PDBe:7t11, PDBj:7t11
PDBsum7t11
PubMed35210615
UniProtP30874|SSR2_HUMAN Somatostatin receptor type 2 (Gene Name=SSTR2);
P41145|OPRK_HUMAN Kappa-type opioid receptor (Gene Name=OPRK1)

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