Structure of PDB 7sym Chain R

Receptor sequence

>7symR (length=142) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence]

GPLQSVQVFGRKKTATAVAHCKRGNGLIKVNGRPLEMIEPRTLQYKLLEP
VLLLGKERFAGVDIRVRVKGGGHVAQIYAIRQSISKALVAYYQKYVDEAS
KKEIKDILIQYDRTLLVADPRRCESKKFGGPGARARYQKSYR

3D structure

PDB

7sym Comprehensive structural overview of the HCV IRES-mediated translation initiation pathway

Chain

Resolution

4.8 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	R	Q11 V12 F13 R15 K17 V22 H24 R69 R71 K73 G74 G75 G76 H77 A79 Q80 R117 R125 R126 E128 S129 K130 K131 F132 A137 R138 A139 Y141 Q142 K143 S144 Y145 R146	Q7 V8 F9 R11 K13 V18 H20 R65 R67 K69 G70 G71 G72 H73 A75 Q76 R113 R121 R122 E124 S125 K126 K127 F128 A133 R134 A135 Y137 Q138 K139 S140 Y141 R142

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364	rRNA processing
GO:0006412	translation
GO:0042274	ribosomal small subunit biogenesis
GO:1990830	cellular response to leukemia inhibitory factor

	Cellular Component
GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005840	ribosome
GO:0022626	cytosolic ribosome
GO:0022627	cytosolic small ribosomal subunit
GO:0032040	small-subunit processome
GO:0045202	synapse
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:7sym, PDBe:7sym, PDBj:7sym
PDBsum	7sym
PubMed
UniProt	G1SGX4\|RS16_RABIT Small ribosomal subunit protein uS9 (Gene Name=RPS16)