Structure of PDB 7r45 Chain R

Receptor sequence
>7r45R (length=95) Species: 9913 (Bos taurus) [Search protein sequence]
GVRTSPTGEKVTHTGQVYDDGDYRKVRFVGRQKEVNENFAIDLIAEQPVS
QVGSRVISCDGGGGALGHPRVYINLDKETKTGTCGYCGLQFRQQH
3D structure
PDB7r45 Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides.
ChainR
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN R C59 H68 C84 C87 C59 H68 C84 C87
Gene Ontology
Biological Process
GO:0006120 mitochondrial electron transport, NADH to ubiquinone
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0045271 respiratory chain complex I

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Biological Process
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Cellular Component
External links
PDB RCSB:7r45, PDBe:7r45, PDBj:7r45
PDBsum7r45
PubMed36701435
UniProtP23934|NDUS6_BOVIN NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (Gene Name=NDUFS6)

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