Structure of PDB 7o72 Chain R

Receptor sequence
>7o72R (length=261) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
EVFDGNDIENNETKVYEESLDLDLERSNRQVWLVRLPMFLAEKWRDRNNL
HGQELGKIRINKDGSKITLLLNENDNDSIPHEYDLELTKKVVENEYVFTE
QNLKKYQRDRYIPYVKTIPKKTAIVGTVCHECQVMPSMNDPNYHKIVEQR
RNIVKLNNKERITTLDETVGVTMSHTGMSMRSDNSNFLKVGREKAKSNIK
SIRMPKKEILDYLFKLFDEYDYWSLKGLKERTRQPEAHLKECLDKVATLV
KYTLRPEYKKL
3D structure
PDB7o72 Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening.
ChainR
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna R N288 K290 S291 I292 R293 P325 N198 K200 S201 I202 R203 P235
BS02 dna R K330 L339 K240 L249
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0000993 RNA polymerase II complex binding
GO:0003677 DNA binding
GO:0005515 protein binding
Biological Process
GO:0001174 transcriptional start site selection at RNA polymerase II promoter
GO:0006355 regulation of DNA-templated transcription
GO:0006366 transcription by RNA polymerase II
GO:0006367 transcription initiation at RNA polymerase II promoter
GO:0006368 transcription elongation by RNA polymerase II
GO:0051123 RNA polymerase II preinitiation complex assembly
Cellular Component
GO:0005634 nucleus
GO:0005674 transcription factor TFIIF complex

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Cellular Component
External links
PDB RCSB:7o72, PDBe:7o72, PDBj:7o72
PDBsum7o72
PubMed34133942
UniProtP41896|T2FB_YEAST Transcription initiation factor IIF subunit beta (Gene Name=TFG2)

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