Structure of PDB 7knu Chain R

Receptor sequence
>7knuR (length=341) Species: 9606 (Homo sapiens) [Search protein sequence]
QLGVTRNKIMTAQYECYQKIMQYCNRTWDGWLCWNDVAAGTESMQLCPDY
FQDFDPSEKVTKICDNWFRHPASNRTWTNYTQCNVNTHEKVKTALNLFYL
TIIGHGLSIASLLISLGIFFYFKSLSCQRITLHKNLFFSFVCNSVVTIIH
LTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFWMLCEGIYLHTLIVVA
VFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTHLLYII
HGPICAALLVNLFFLLNIVRVLITKNLYMKAVRATLILVPLLGIEFVLIP
WEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQY
3D structure
PDB7knu Structure and dynamics of the CGRP receptor in apo and peptide-bound forms.
ChainR
Resolution3.49 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide R D70 W72 F92 Q93 D94 H114 S117 W121 T122 Y124 N128 D29 W31 F51 Q52 D53 H70 S73 W77 T78 Y80 N84
Gene Ontology
Molecular Function
GO:0004888 transmembrane signaling receptor activity
GO:0004930 G protein-coupled receptor activity
GO:0004948 calcitonin receptor activity
Biological Process
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G protein-coupled receptor signaling pathway
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7knu, PDBe:7knu, PDBj:7knu
PDBsum7knu
PubMed33602864
UniProtQ16602|CALRL_HUMAN Calcitonin gene-related peptide type 1 receptor (Gene Name=CALCRL)

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