Structure of PDB 7jqc Chain R

Receptor sequence

>7jqcR (length=142) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence]

GPLQSVQVFGRKKTATAVAHCKRGNGLIKVNGRPLEMIEPRTLQYKLLEP
VLLLGKERFAGVDIRVRVKGGGHVAQIYAIRQSISKALVAYYQKYVDEAS
KKEIKDILIQYDRTLLVADPRRCESKKFGGPGARARYQKSYR

3D structure

PDB

7jqc Nonstructural Protein 1 of SARS-CoV-2 Is a Potent Pathogenicity Factor Redirecting Host Protein Synthesis Machinery toward Viral RNA.

Chain

Resolution

3.3 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	R	Q11 V12 F13 K17 T18 V22 H24 K26 K33 N35 R71 K73 G75 G76 H77 V78 A79 P124 R125 R126 C127 E128 S129 K130 K131 F132 G136 A137 R138 R140 Y141 Q142 K143 R146	Q7 V8 F9 K13 T14 V18 H20 K22 K29 N31 R67 K69 G71 G72 H73 V74 A75 P120 R121 R122 C123 E124 S125 K126 K127 F128 G132 A133 R134 R136 Y137 Q138 K139 R142

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364	rRNA processing
GO:0006412	translation
GO:0042274	ribosomal small subunit biogenesis
GO:1990830	cellular response to leukemia inhibitory factor

	Cellular Component
GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005840	ribosome
GO:0022626	cytosolic ribosome
GO:0022627	cytosolic small ribosomal subunit
GO:0032040	small-subunit processome
GO:0045202	synapse
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:7jqc, PDBe:7jqc, PDBj:7jqc
PDBsum	7jqc
PubMed	33188728
UniProt	G1SGX4\|RS16_RABIT Small ribosomal subunit protein uS9 (Gene Name=RPS16)