Structure of PDB 7f16 Chain R

Receptor sequence
>7f16R (length=376) Species: 9606 (Homo sapiens) [Search protein sequence]
TITIEEQIVLVLKAKVQCELNITAQLQEGEGNCFPEWDGLICWPRGTVGK
ISAVPCPPYIYDFNHKGVAFRHCNPNGTWDFMHSLNKTWANYSDCLRFLQ
PDISIGKQEFFERLYVMYTVGYSISFGSLAVAILIIGYFRRLHCTRNYIH
MHLFVSFMLRATSIFVKDRVVHAHIGVKELESQYIGCKIAVVMFIYFLAT
NYYWILVEGLYLHNLIFVAFFSDTKYLWGFILIGWGFPAAFVAAWAVARA
TLADARCWELSAGDIKWIYQAPILAAIGLNFILFLNTVRVLATKIWETDT
RKQYRKLAKSTLVLVLVFGVHYIVFVCLPGLGWEIRMHCELFFNSFQGFF
VSIIYCYCNGEVQAEVKKMWSRWNLS
3D structure
PDB7f16 Molecular insights into differentiated ligand recognition of the human parathyroid hormone receptor 2.
ChainR
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CLR R W316 A320 W267 A271
BS02 CLR R D313 I317 A320 P321 D264 I268 A271 P272
Gene Ontology
Molecular Function
GO:0004888 transmembrane signaling receptor activity
GO:0004930 G protein-coupled receptor activity
Biological Process
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G protein-coupled receptor signaling pathway
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7f16, PDBe:7f16, PDBj:7f16
PDBsum7f16
PubMed34353904
UniProtP49190|PTH2R_HUMAN Parathyroid hormone 2 receptor (Gene Name=PTH2R)

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