Structure of PDB 6zvi Chain R

Receptor sequence
>6zviR (length=313) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
LVLRGTLEGHNGWVTSLATSAGQPNLLLSASRDKTLISWKLTGDDQKFGV
PVRSFKGHSHIVQDCTLTADGAYALSASWDKTLRLWDVATGETYQRFVGH
KSDVMSVDIDKKASMIISGSRDKTIKVWTIKGQCLATLLGHNDWVSQVRV
VPNEAADDDSVTIISAGNDKMVKAWNLNQFQIEADFIGHNSNINTLTASP
DGTLIASAGKDGEIMLWNLAAKKAMYTLSAQDEVFSLAFSPNRYWLAAAT
ATGIKVFSLDPQYLVDDLRPEFAGYSKAAEPHAVSLAWSADGQTLFAGYT
DNVIRVWQVMTAN
3D structure
PDB6zvi EDF1 coordinates cellular responses to ribosome collisions.
ChainR
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna R N17 S65 H66 R102 Y281 S282 A285 N11 S59 H60 R96 Y275 S276 A279
Gene Ontology
Molecular Function
GO:0001965 G-protein alpha-subunit binding
GO:0005080 protein kinase C binding
GO:0005092 GDP-dissociation inhibitor activity
GO:0043022 ribosome binding
GO:0045182 translation regulator activity
Biological Process
GO:0002181 cytoplasmic translation
GO:0006521 regulation of cellular amino acid metabolic process
GO:0007186 G protein-coupled receptor signaling pathway
GO:0010629 negative regulation of gene expression
GO:0017148 negative regulation of translation
GO:0061157 mRNA destabilization
GO:0070651 nonfunctional rRNA decay
GO:0072344 rescue of stalled ribosome
GO:1902660 negative regulation of glucose mediated signaling pathway
GO:1990116 ribosome-associated ubiquitin-dependent protein catabolic process
GO:1990145 maintenance of translational fidelity
GO:2001125 negative regulation of translational frameshifting
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6zvi, PDBe:6zvi, PDBj:6zvi
PDBsum6zvi
PubMed32744497
UniProtP38011|GBLP_YEAST Small ribosomal subunit protein RACK1 (Gene Name=ASC1)

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