Structure of PDB 6vsu Chain R

Receptor sequence
>6vsuR (length=316) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
SSIEKGQNRVIDASLTLIRERAKLKGELVRLLGGAKASTSLLGVPLGHNS
SFLQGPAFAPPRIREAIWCGSTNSATEEGKELKDPRVLTDVGDVPVQEIR
DCGVDDDRLMNVISESVKLVMEEEPLRPLVLGGDHSISYPVVRAVSEKLG
GPVDILHLDAHPDIYDCFEGNKYSHASSFARIMEGGYARRLLQVGIRSIN
QEGREQGKRFGVEQYEMRTFSKDRPMLENLKLGEGVKGVYISIDVDCLDP
AFAPGVSHIEPGGLSFRDVLNILHNLQADVVGADVVEFNPQRDTVDGMTA
MVAAKLVRELAAKISK
3D structure
PDB6vsu The Neighboring Subunit Is Engaged to Stabilize the Substrate in the Active Site of Plant Arginases.
ChainR
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.3.1: arginase.
3.5.3.11: agmatinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN R D185 H187 D270 D272 D159 H161 D244 D246
BS02 MN R H161 D185 D189 D270 H135 D159 D163 D244
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004053 arginase activity
GO:0008783 agmatinase activity
GO:0016787 hydrolase activity
GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
GO:0046872 metal ion binding
GO:0050897 cobalt ion binding
Biological Process
GO:0000050 urea cycle
GO:0006525 arginine metabolic process
GO:0006527 arginine catabolic process
GO:0009446 putrescine biosynthetic process
GO:0033388 putrescine biosynthetic process from arginine
GO:0033389 putrescine biosynthetic process from arginine, using agmatinase
GO:0034214 protein hexamerization
Cellular Component
GO:0005739 mitochondrion
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6vsu, PDBe:6vsu, PDBj:6vsu
PDBsum6vsu
PubMed32754173
UniProtP46637|ARGI1_ARATH Arginase 1, mitochondrial (Gene Name=ARGAH1)

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