Structure of PDB 6tb3 Chain R

Receptor sequence

>6tb3R (length=216) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]

GWVPVTKLGRLVKAGKITTIEEIFLHSLPVKEFQIIDTLLPGLQDEVMNI
KPVQKQTRAGQRTRFKAVVVVGDSNGHVGLGIKTAKEVAGAIRAGIIIAK
LSVIPIRRGYWGTNLGQPHSLATKTTGKCGSVTVRLIPAPRGSGIVASPA
VKKLLQLAGVEDVYTQSNGKTRTLENTLKAAFVAIGNTYGFLTPNLWAEQ
PLPVSPLDIYSDEASA

3D structure

PDB

6tb3 The Ccr4-Not complex monitors the translating ribosome for codon optimality.

Chain

Resolution

2.8 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	R	K84 V86 Q87 K88 Q89 T90 R91 Q94 K99 K119 T159 K161 C162 S164 R168 V179 A180 Y197 T198 Q199 S200 N201 K203 T204 R205 T206 N209 K212	K51 V53 Q54 K55 Q56 T57 R58 Q61 K66 K86 T126 K128 C129 S131 R135 V146 A147 Y164 T165 Q166 S167 N168 K170 T171 R172 T173 N176 K179

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome
GO:0015935	small ribosomal subunit

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:6tb3, PDBe:6tb3, PDBj:6tb3
PDBsum	6tb3
PubMed	32299921
UniProt	P25443\|RS2_YEAST Small ribosomal subunit protein uS5 (Gene Name=RPS2)

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