Structure of PDB 6r7n Chain R

Receptor sequence
>6r7nR (length=86) Species: 9606 (Homo sapiens) [Search protein sequence]
AKKKRFEVKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSE
ECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWE
3D structure
PDB6r7n Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome.
ChainR
Resolution6.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
2.3.2.32: cullin-RING-type E3 NEDD8 transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN R D51 L52 D35 L36
BS02 ZN R I49 E66 E67 C68 V70 I33 E50 E51 C52 V54
BS03 ZN R E55 F81 E39 F65
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:6r7n, PDBe:6r7n, PDBj:6r7n
PDBsum6r7n
PubMed31444342
UniProtP62877|RBX1_HUMAN E3 ubiquitin-protein ligase RBX1 (Gene Name=RBX1)

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