Structure of PDB 6qun Chain R

Receptor sequence
>6qunR (length=334) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
KIRIGINGFGRIGRLVARVVLQRDDVELVAVNDPFITTEYMTYMFKYDSV
HGQWKHNELKIKDEKTLLFGEKPVTVFGIRNPEDIPWAEAGADYVVESTG
VFTDKDKAAAHLKGGAKKVVISAPSKDAPMFVVGVNEHEYKSDLDIVSNA
SCTTNCLAPLAKVINDRFGIVEGLMTTVHSITATQKTVDGPSMKDWRGGR
AASFNIIPSSTGAAKAVGKVLPALNGKLTGMSFRVPTVDVSVVDLTVRLE
KAATYDEIKKAIKEESEGKLKGILGYTEDDVVSTDFVGDNRSSIFDAKAG
IALSDKFVKLVSWYDNEWGYSSRVVDLIVHMSKA
3D structure
PDB6qun Glutathionylation primes soluble glyceraldehyde-3-phosphate dehydrogenase for late collapse into insoluble aggregates.
ChainR
Resolution3.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) C149 H176
Catalytic site (residue number reindexed from 1) C152 H179
Enzyme Commision number 1.2.1.12: glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD R N6 G7 G9 R10 I11 N31 D32 P33 T96 G97 F99 S119 A149 A180 N313 Y317 N7 G8 G10 R11 I12 N32 D33 P34 T99 G100 F102 S122 A152 A183 N316 Y320
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GO:0005507 copper ion binding
GO:0005515 protein binding
GO:0008886 glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity
GO:0016491 oxidoreductase activity
GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
GO:0050661 NADP binding
GO:0051287 NAD binding
GO:1901149 salicylic acid binding
Biological Process
GO:0006006 glucose metabolic process
GO:0006094 gluconeogenesis
GO:0006096 glycolytic process
GO:0006979 response to oxidative stress
GO:0009408 response to heat
GO:0009744 response to sucrose
GO:0010154 fruit development
GO:0042542 response to hydrogen peroxide
GO:0045893 positive regulation of DNA-templated transcription
GO:0048316 seed development
GO:0051775 response to redox state
Cellular Component
GO:0000325 plant-type vacuole
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005740 mitochondrial envelope
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0009507 chloroplast
GO:0048046 apoplast

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6qun, PDBe:6qun, PDBj:6qun
PDBsum6qun
PubMed31772010
UniProtP25858|G3PC1_ARATH Glyceraldehyde-3-phosphate dehydrogenase GAPC1, cytosolic (Gene Name=GAPC1)

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