Structure of PDB 6qno Chain R
Receptor sequence
>6qnoR (length=334) Species:
9913
(Bos taurus) [
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CGTEGPNFYVPFSNKTGVVRSPFEAPQYYLAEPWQFSMLAAYMFLLIMLG
FPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHG
YFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGEN
HAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNE
SFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVT
RMVIIYVIAFLICWLPYAGVAFYIFTHQGSCFGPIFMTIPAFFAKTSAVY
NPVIYIMMNKQFRNCMVTTLCCGKNPLGDDEAST
3D structure
PDB
6qno
Cryo-EM structure of the rhodopsin-G alpha i-beta gamma complex reveals binding of the rhodopsin C-terminal tail to the G beta subunit.
Chain
R
Resolution
4.38 Å
3D
structure
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Enzymatic activity
Enzyme Commision number
?
Interaction with ligand
Site
#
Ligand
Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01
RET
R
Y191 M207 F208 W265 Y268 A269 K296
Y190 M206 F207 W264 Y267 A268 K295
Gene Ontology
Molecular Function
GO:0001965
G-protein alpha-subunit binding
GO:0002046
opsin binding
GO:0004930
G protein-coupled receptor activity
GO:0005085
guanyl-nucleotide exchange factor activity
GO:0005502
11-cis retinal binding
GO:0005515
protein binding
GO:0008020
G protein-coupled photoreceptor activity
GO:0008270
zinc ion binding
GO:0009881
photoreceptor activity
GO:0042802
identical protein binding
GO:0046872
metal ion binding
GO:1990763
arrestin family protein binding
Biological Process
GO:0000226
microtubule cytoskeleton organization
GO:0007186
G protein-coupled receptor signaling pathway
GO:0007601
visual perception
GO:0007602
phototransduction
GO:0007603
phototransduction, visible light
GO:0009416
response to light stimulus
GO:0009583
detection of light stimulus
GO:0009642
response to light intensity
GO:0010467
gene expression
GO:0016038
absorption of visible light
GO:0016056
G protein-coupled opsin signaling pathway
GO:0043052
thermotaxis
GO:0045494
photoreceptor cell maintenance
GO:0050953
sensory perception of light stimulus
GO:0050960
detection of temperature stimulus involved in thermoception
GO:0060041
retina development in camera-type eye
GO:0071482
cellular response to light stimulus
GO:0071800
podosome assembly
GO:1904389
rod bipolar cell differentiation
Cellular Component
GO:0000139
Golgi membrane
GO:0001750
photoreceptor outer segment
GO:0001917
photoreceptor inner segment
GO:0005794
Golgi apparatus
GO:0005886
plasma membrane
GO:0005911
cell-cell junction
GO:0016020
membrane
GO:0019867
outer membrane
GO:0042622
photoreceptor outer segment membrane
GO:0042995
cell projection
GO:0060342
photoreceptor inner segment membrane
GO:0097225
sperm midpiece
GO:0097381
photoreceptor disc membrane
GO:0097648
G protein-coupled receptor complex
GO:0120200
rod photoreceptor outer segment
GO:1990913
sperm head plasma membrane
View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB
RCSB:6qno
,
PDBe:6qno
,
PDBj:6qno
PDBsum
6qno
PubMed
31251171
UniProt
P02699
|OPSD_BOVIN Rhodopsin (Gene Name=RHO)
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