Structure of PDB 6niy Chain R

Receptor sequence
>6niyR (length=261) Species: 9606 (Homo sapiens) [Search protein sequence]
TPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIFVFFRSLGCQRVTLHKNM
FLTYILNSMIIIIHLVEVVSCKILHFFHQYMMACNYFWMLCEGIYLHTLI
VVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCWLSVETHLL
YIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHMYLKAVKATMILVPLLG
IQFVVFPWRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVK
RQWAQFKIQWN
3D structure
PDB6niy The Molecular Control of Calcitonin Receptor Signaling.
ChainR
Resolution3.34 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide R L148 H201 L291 V293 E294 L298 Y299 H302 F359 P360 W361 H377 L11 H64 L143 V145 E146 L150 Y151 H154 F206 P207 W208 H224
Gene Ontology
Molecular Function
GO:0004888 transmembrane signaling receptor activity
GO:0004930 G protein-coupled receptor activity
GO:0004948 calcitonin receptor activity
Biological Process
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G protein-coupled receptor signaling pathway
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6niy, PDBe:6niy, PDBj:6niy
PDBsum6niy
PubMed32219215
UniProtP30988|CALCR_HUMAN Calcitonin receptor (Gene Name=CALCR)

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