Structure of PDB 5khd Chain R

Receptor sequence
>5khdR (length=73) Species: 953739 (Streptomyces venezuelae ATCC 10712) [Search protein sequence]
PKLVLDLERLAHVPQEKAGPLQRYAATIQSQRGDYNGKVLSIRQDDLRTL
AVIYDQSPSVLTEQLISWGVLDA
3D structure
PDB5khd Tetrameric c-di-GMP mediates effective transcription factor dimerization to control Streptomyces development.
ChainR
Resolution1.7501 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 C2E R K84 R114 S123 I124 R125 Q126 K2 R32 S41 I42 R43 Q44 MOAD: Kd=2.5uM
PDBbind-CN: -logKd/Ki=5.60,Kd=2.5uM
BS02 C2E R D116 N118 V121 L122 S123 D34 N36 V39 L40 S41 MOAD: Kd=2.5uM
PDBbind-CN: -logKd/Ki=5.60,Kd=2.5uM
BS03 C2E R I110 R114 R125 D128 I28 R32 R43 D46 MOAD: Kd=2.5uM
PDBbind-CN: -logKd/Ki=5.60,Kd=2.5uM
BS04 C2E R R114 G115 D116 R32 G33 D34 MOAD: Kd=2.5uM
PDBbind-CN: -logKd/Ki=5.60,Kd=2.5uM
Gene Ontology
Biological Process
GO:0045892 negative regulation of DNA-templated transcription

View graph for
Biological Process
External links
PDB RCSB:5khd, PDBe:5khd, PDBj:5khd
PDBsum5khd
PubMed25171413
UniProtF2RCL8

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