Structure of PDB 3d48 Chain R

Receptor sequence
>3d48R (length=195) Species: 9606 (Homo sapiens) [Search protein sequence]
LPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNYSLTYHREGETLMHEC
PDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIV
QPDPPLELAVEVKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEWE
IHFAGQQTEFKILSPGQKYLVQVRCKPDHGYWSAWSPATFIQIPS
3D structure
PDB3d48 Crystal structure of a prolactin receptor antagonist bound to the extracellular domain of the prolactin receptor
ChainR
Resolution2.5 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CO3 R Y190 W191 Y181 W182
BS02 CO3 R C12 R13 C11 R12
BS03 CO3 R T39 Y40 H41 T38 Y39 H40
Gene Ontology
Molecular Function
GO:0004896 cytokine receptor activity
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:3d48, PDBe:3d48, PDBj:3d48
PDBsum3d48
PubMed18467331
UniProtP16471|PRLR_HUMAN Prolactin receptor (Gene Name=PRLR)

[Back to BioLiP]