Structure of PDB 2om1 Chain R
Receptor sequence
>2om1R (length=30) Species:
9606
(Homo sapiens) [
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FVNQHLCGSHLVEALYLVCGERGFFYTPKT
3D structure
PDB
2om1
Crystallographic characterization of two novel crystal forms of human insulin induced by chaotropic agents and a shift in pH.
Chain
R
Resolution
1.97 Å
3D
structure
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Enzymatic activity
Enzyme Commision number
?
Interaction with ligand
Site
#
Ligand
Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01
peptide
R
Q4 C7 L11 L15 V18 C19 R22 G23 F24 Y26 T30
Q4 C7 L11 L15 V18 C19 R22 G23 F24 Y26 T30
BS02
peptide
R
F1 V2
F1 V2
BS03
peptide
R
N3 L6 H10
N3 L6 H10
BS04
peptide
R
H5 G8 S9 V12 Y16 E21 G23 F24 F25 Y26
H5 G8 S9 V12 Y16 E21 G23 F24 F25 Y26
BS05
peptide
R
E13 L17
E13 L17
BS06
RCO
R
H10 L11
H10 L11
Gene Ontology
Molecular Function
GO:0005179
hormone activity
Cellular Component
GO:0005576
extracellular region
View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB
RCSB:2om1
,
PDBe:2om1
,
PDBj:2om1
PDBsum
2om1
PubMed
18093308
UniProt
P01308
|INS_HUMAN Insulin (Gene Name=INS)
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