Structure of PDB 1j0x Chain R

Receptor sequence
>1j0xR (length=332) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence]
VKVGVNGFGRIGRLVTRAAFNSGKVDVVAINDPFIDLHYMVYMFQYDSTH
GKFHGTVKAENGKLVINGKAITIFQERDPANIKWGDAGAEYVVESTGVFT
TMEKAGAHLKGGAKRVIISAPSADAPMFVMGVNHEKYDNSLKIVSNASCT
TNCLAPLAKVIHDHFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGAA
QNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTPNVSVVDLTCRLEKAA
KYDDIKKVVKQASEGPLKGILGYTEDQVVSCDFNSDTHSSTFDAGAGIAL
NDHFVKLISWYDNEFGYSNRVVDLMVHMASKE
3D structure
PDB1j0x Structure of rabbit-muscle glyceraldehyde-3-phosphate dehydrogenase.
ChainR
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.2.1.12: glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).
2.6.99.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD R F8 G9 R10 I11 D32 P33 T96 G97 S119 C149 Y317 F8 G9 R10 I11 D32 P33 T96 G97 S119 C149 Y317 MOAD: Kd=0.01uM
Gene Ontology
Molecular Function
GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GO:0005515 protein binding
GO:0008017 microtubule binding
GO:0016491 oxidoreductase activity
GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
GO:0016740 transferase activity
GO:0035605 peptidyl-cysteine S-nitrosylase activity
GO:0050661 NADP binding
GO:0051287 NAD binding
Biological Process
GO:0000226 microtubule cytoskeleton organization
GO:0006006 glucose metabolic process
GO:0006096 glycolytic process
GO:0006417 regulation of translation
GO:0006915 apoptotic process
GO:0032481 positive regulation of type I interferon production
GO:0035606 peptidyl-cysteine S-trans-nitrosylation
GO:0043123 positive regulation of canonical NF-kappaB signal transduction
GO:0045087 innate immune response
GO:0050821 protein stabilization
GO:0051402 neuron apoptotic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0015630 microtubule cytoskeleton
GO:0097452 GAIT complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1j0x, PDBe:1j0x, PDBj:1j0x
PDBsum1j0x
PubMed14646080
UniProtP46406|G3P_RABIT Glyceraldehyde-3-phosphate dehydrogenase (Gene Name=GAPDH)

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