Structure of PDB 8iuj Chain QC

Receptor sequence

>8iujQC (length=364) Species: 3039 (Euglena gracilis)

NKISLYRSYSTTILLSPAYSLGFCASIFIVIQIISGYILASNYIASTNES
FNIIHNVIMRELDTGWLIRFNHINGCAFLFIVIYMHIYRSLYHNSITKTS
VWIVGIIMYILICGIAFTGYSLVYGQMSLWAIVVICSLVTAIPFIGNKLL
ILIWGGNIVSSVTLQRIFCIHYLLPLLLILFIIIHLYNLHNVNSTGDNYF
INNRYDRINFYPLLLIRDVFIGSNILIIYNIFVYYYSDLFGHPDNYVPAN
PLVTPSEIMPEFYLLPFYALIRAIPHKVLGIIIMVLFLLSLTNLYPIYFI
RFYNNINILQRSLLLLLLLDLVIASKLCLLINHYESFYLLLILSILCVLS
HHIYNTSFNFSNSI

3D structure

• PDB: 8iuj Euglena's atypical respiratory chain adapts to the discoidal cristae and flexible metabolism.
• Chain: QC
• Resolution: 3.06 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	HEM	QC	Q33 G37 L40 R70 H73 I74 C77 I116 G120 L123 V124 H172 P176	Q32 G36 L39 R69 H72 I73 C76 I115 G119 L122 V123 H171 P175
BS02	HEM	QC	Y20 G23 I84 H87 I88 S91 S96 V102 W103 G106 I107 M109 H186 L187 L190 S195 T196	Y19 G22 I83 H86 I87 S90 S95 V101 W102 G105 I106 M108 H185 L186 L189 S194 T195

Gene Ontology

Molecular Function

• GO:0009055 electron transfer activity
• GO:0016491 oxidoreductase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0022900 electron transport chain
• GO:0022904 respiratory electron transport chain

Cellular Component

• GO:0005739 mitochondrion
• GO:0005743 mitochondrial inner membrane
• GO:0016020 membrane

External links

• PDB: RCSB:8iuj, PDBe:8iuj, PDBj:8iuj
• PDBsum: 8iuj
• PubMed: 38388527
• UniProt: A0A0S2YRT7