Structure of PDB 9gaw Chain Q

Receptor sequence

>9gawQ (length=505) Species: 9606 (Homo sapiens) [Search protein sequence]

MNLERLRKRVRQYLDQQQYQSALFWADKVASLSREEPQDIYWLAQCLYLT
AQYHRAAHALRSRKLDKLYEACRYLAARCHYAAKEHQQALDVLDMSQSSI
KSSICLLRGKIYDALDNRTLATYSYKEALKLDVYCFEAFDLLTSHHMLTA
QEEKELLESLPLSKLCNEEQELLRFLFENKLKKYNKPSETVIPESVDGLQ
ENLDVVVSLAERHYYNCDFKMCYKLTSVVMEKDPFHASCLPVHIGTLVEL
NKANELFYLSHKLVDLYPSNPVSWFAVGCYYLMVGHKNEHARRYLSKATT
LEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEY
GLTNNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQNGEWKTAEKWFLDA
LEKIKAIGNEVTVDKWEPLLNNLGHVCRKLKKYAEALDYHRQALVLIPQN
ASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLGHCIEMYIG
DSEAY

3D structure

PDB

9gaw High-resolution structure of the Anaphase-promoting complex (APC/C) bound to co-activator Cdh1

Chain

Resolution

2.9 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	Q	Y242 Y243 I338 H342 A345 Y357 Y373 L376 E377 F403 H406 E407 V410 F413 E445 N449 N450 H453 R456 K457 N478 T481 Y487 F514 M518 M525	Y214 Y215 I310 H314 A317 Y329 Y345 L348 E349 F375 H378 E379 V382 F385 E417 N421 N422 H425 R428 K429 N450 T453 Y459 F486 M490 M497

External links

PDB	RCSB:9gaw, PDBe:9gaw, PDBj:9gaw
PDBsum	9gaw
PubMed
UniProt	Q13042\|CDC16_HUMAN Cell division cycle protein 16 homolog (Gene Name=CDC16)

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