Structure of PDB 8xon Chain Q

Receptor sequence

>8xonQ (length=592) Species: 67305 (Streptomyces hawaiiensis)

SLVLDQFGRNLTQAARESKLDPVIGREKEIERVMQVLSRRTKNNPVLIGE
PGVGKTAVVEGLAQAIVKGEVPETLKDKHLYTLDLGALVAGSRYRGDFEE
RLKKVLKEIRTRGDIILFIDALHTLVGAGAAEGAIDAASILKPMLARGEL
QTIGATTLDEYRKHLEKDAALERRFQPIQVAEPSLPHTIEILKGLRDRYE
AHHRVSITDEALVQAATLADRYISDRFLPDKAIDLIDEAGSRMRIRRVAE
VDGELIAEVLATATGIPVFKLTEEESSRLLRMEDELHKRVIGQVDAVKAL
SKAIRRTRAGLKDPKRPGGSFIFAGPSGVGKTELSKALAEFLFGDEDALI
SLDMSEFSEKHTVSRLFGSPPGYVGYEEGGQLTEKVRRKPFSVVLFDAVE
KAHPDIFNSLLQILEDGRLTDSQGRVVDFKNTVIIMTTNLGTRDISKGFN
LGFAAQGDTKSNYERMKNKVSDELKQHFRPEFLNRVDDVVVFPQLSQADI
LKIVDLMIDKVDERLKDRDMGIELSSSAKELLSKKGYDPVLGARPLRRTI
QREIEDSLSEKILFGELRPGHIVVVDTEGEGETKTFTFRGEE

3D structure

• PDB: 8xon Structural insights into the Clp protein degradation machinery.
• Chain: Q
• Resolution: 1.96 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	Q	R256 Y257 R258 E295 G596 Y597 V598	R93 Y94 R95 E132 G372 Y373 V374
BS02	ATP	Q	R336 R337	R173 R174
BS03	ADP	Q	V186 I187 G215 G217 K218 T219 A220 I354	V23 I24 G52 G54 K55 T56 A57 I191
BS04	ATP	Q	V514 I515 G552 V553 G554 K555 T556 E557 N663 I727 R768	V290 I291 G328 V329 G330 K331 T332 E333 N439 I503 R544

Gene Ontology

Molecular Function

• GO:0005524 ATP binding
• GO:0016887 ATP hydrolysis activity

External links

• PDB: RCSB:8xon, PDBe:8xon, PDBj:8xon
• PDBsum: 8xon
• PubMed: 38501868
• UniProt: A0A6G5RIJ6