Structure of PDB 8s4g Chain Q

Receptor sequence

>8s4gQ (length=506) [Search protein sequence]

MNLERLRKRVRQYLDQQQYQSALFWADKVASLSREEPQDIYWLAQCLYLT
AQYHRAAHALRSRKLDKLYEACRYLAARCHYAAKEHQQALDVLDMMSQSS
IKSSICLLRGKIYDALDNRTLATYSYKEALKLDVYCFEAFDLLTSHHMLT
AQEEKELLESLPLSKLCNEEQELLRFLFENKLKKYNKPSETVIPESVDGL
QENLDVVVSLAERHYYNCDFKMCYKLTSVVMEKDPFHASCLPVHIGTLVE
LNKANELFYLSHKLVDLYPSNPVSWFAVGCYYLMVGHKNEHARRYLSKAT
TLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLE
YGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQNGEWKTAEKWFLD
ALEKIKAIGNEVTVDKWEPLLNNLGHVCRKLKKYAEALDYHRQALVLIPQ
NASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLGHCIEMYI
GDSEAY

3D structure

PDB

8s4g New structural features of the APC/C revealed by high resolution cryo-EM structures of apo-APC/C and the APC/C-CDH1-EMI1 complex

Chain

Resolution

Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	Q	Y242 Y243 V276 I338 H342 A345 Y357 Y373 L376 E377 F403 H406 V410 F413 K443 E445 N449 N450 H453 R456 K457 N478 T481 Y487 S490 L491 F514 M518 M525	Y215 Y216 V249 I311 H315 A318 Y330 Y346 L349 E350 F376 H379 V383 F386 K416 E418 N422 N423 H426 R429 K430 N451 T454 Y460 S463 L464 F487 M491 M498

External links

PDB	RCSB:8s4g, PDBe:8s4g, PDBj:8s4g
PDBsum	8s4g
PubMed

[Back to BioLiP]