Structure of PDB 8g6e Chain Q

Receptor sequence
>8g6eQ (length=242) Species: 5843 (Plasmodium falciparum NF54) [Search protein sequence]
ARRYDSRTTTFSPEGRLYQVEYALEAINNASITIGLITKDGVILGADKVF
ISKLIDKANNYEKIYKIDKHIFCGVAGLNADANILINQSRLYAQRYLYNY
NEVQPVSQLVVQICDIKQSYTQYGGLRPYGVSFLIGGYDTKDGYQLYHTD
PSGNYSGWFATAIGTNNLTASSVLKQEWKNDMTLEEGLLLALKTLAKSTD
TEIPKSEKIELAYLTNKDGEVYQKYLTEKEIEELIKLYTQKY
3D structure
PDB8g6e Structures revealing mechanisms of resistance and collateral sensitivity of Plasmodium proteasome inhibitors
ChainQ
Resolution2.18 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 YRE Q R96 Y99 N100 R95 Y98 N99
Gene Ontology
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0010498 proteasomal protein catabolic process
GO:0051603 proteolysis involved in protein catabolic process
Cellular Component
GO:0000502 proteasome complex
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005839 proteasome core complex
GO:0019773 proteasome core complex, alpha-subunit complex

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Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8g6e, PDBe:8g6e, PDBj:8g6e
PDBsum8g6e
PubMed38097652
UniProtW7KN95

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