Structure of PDB 8cs9 Chain Q

Receptor sequence
>8cs9Q (length=390) Species: 9606 (Homo sapiens) [Search protein sequence]
MRFTFPLMAIVLEIAMIVLFGLFVEYIFFELYPLFQDVHVMIFVGFGFLM
TFLKKYGFSSVGINLLVAALGLQWGTIVQGILQSQGQKFNIGIKNMINAD
FSAATVLISFGAVLGKTSPTQMLIMTILEIVFFAHNEYLVSEIFKASDIG
ASMTIHAFGAYFGLAVAGILYRSGLRKGHENEESAYYSDLFAMIGTLFLW
MFWPSFNSAIAEPGDKQCRAIVNTYFSLAACVLTAFAFSSLVEHRGKLNM
VHIQNATLAGGVAVGTCADMAIHPFGSMIIGSIAGMVSVLGYKFLTPLFT
TKLRIHDTCGVHNLHGLPGVVGGLAGIVAVAMGASNTSMAMQAAALGSSI
GTAVVGGLMTGLILKLPLWGQPSDQNCYDDSVYWKVPKTR
3D structure
PDB8cs9 Architecture of the human erythrocyte ankyrin-1 complex.
ChainQ
Resolution2.74 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AJP Q I291 F294 V340 A344 V347 M351 I272 F275 V321 A325 V328 M332
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008519 ammonium channel activity
GO:0015200 methylammonium transmembrane transporter activity
GO:0022840 leak channel activity
GO:0030506 ankyrin binding
GO:0035379 carbon dioxide transmembrane transporter activity
Biological Process
GO:0006873 intracellular monoatomic ion homeostasis
GO:0015670 carbon dioxide transport
GO:0015701 bicarbonate transport
GO:0035378 carbon dioxide transmembrane transport
GO:0048821 erythrocyte development
GO:0060586 multicellular organismal-level iron ion homeostasis
GO:0072488 ammonium transmembrane transport
GO:0072489 methylammonium transmembrane transport
GO:0097272 ammonium homeostasis
GO:0098662 inorganic cation transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0170014 ankyrin-1 complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8cs9, PDBe:8cs9, PDBj:8cs9
PDBsum8cs9
PubMed35835865
UniProtQ02094|RHAG_HUMAN Ammonium transporter Rh type A (Gene Name=RHAG)

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