Structure of PDB 8cq7 Chain Q

Receptor sequence

>8cq7Q (length=127) Species: 5476 (Candida albicans)

SQVFGVARIFASFNDTFVHVTDLSGKETIARVTGGMKVKADRDESSPYAA
MLAAQDVAAKCKEVGITAVHIKLRATGGTKTKTPGPGGQSALRALARSGL
RIGRIEDVTPVPSDSTRRKGGRRGRRL

3D structure

• PDB: 8cq7 Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement
• Chain: Q
• Resolution: 3.2 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	Q	R13 N19 D20 F22 H24 S29 G30 K31 E32 T33 R36 T38 G40 M41 D46 R47 E49 R79 G83 V116 P117 S118 D119 R122 K124 G126 R127 R128 R130 R131 L132	R8 N14 D15 F17 H19 S24 G25 K26 E27 T28 R31 T33 G35 M36 D41 R42 E44 R74 G78 V111 P112 S113 D114 R117 K119 G121 R122 R123 R125 R126 L127
BS02	MG	Q	N19 E49	N14 E44

External links

• PDB: RCSB:8cq7, PDBe:8cq7, PDBj:8cq7
• PDBsum: 8cq7
• UniProt: A0A8H6F0V4