Structure of PDB 7rl5 Chain Q

Receptor sequence

>7rl5Q (length=559) Species: 4932 (Saccharomyces cerevisiae)

MKYVVVSGGVISGIGKGVLASSTGMLLKTLGLKVTSIKIDPYMNIDAGTM
SPLEHGECFVLDDGGETDLDLGNYERYLGITLSRDHNITTGKIYSHVISR
ERRGDYLGKTVQIVPHLTNAIQDWIQRVSKIPVDDTGLEPDVCIIELGGT
VGDIESAPFVEALRQFQFEVGRENFALIHVSLVPVIHGEQKTKPTQAAIK
DLRSLGLIPDMIACRCSEELNRSTIDKIAMFCHVGPEQVVNVHDVNSTYH
VPLLLLKQHMIDYLHSRLKLGEVPLTLEDKERGSQLLTNWENMTKNLDDS
DDVVKIALVGKYTNLKDSYLSVTKSLEHASMKCRRQLEILWVEASNLEPE
TQEVDKNKFHDSWNKLSSADGILVPGGFGTRGIEGMILAAKWARESGVPF
LGVCLGLQVAAIEFARNVIGRPNSSSTEFLDETLLAPEDQVVITMRLGLR
PTIFQPNSEWSNIRKLYGEVNEVHERHRHRYEINPKIVNDMESRGFIFVG
KDETGQRCEIFELKGHPYYVGTQYHPEYTSKVLEPSRPFWGLVAAASGTL
GEVIKDINL

3D structure

• PDB: 7rl5 Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation.
• Chain: Q
• Resolution: 3.8 Å

Enzymatic activity

• Enzyme Commision number: 6.3.4.2: CTP synthase (glutamine hydrolyzing).

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	CTP	Q	Q112 E161	Q112 E161
BS02	CTP	Q	K16 G17 V18 Y77 K324	K16 G17 V18 Y77 K324
BS03	CTP	Q	S12 D153 I154 E155	S12 D153 I154 E155
BS04	CTP	Q	K191 T192	K191 T192

Gene Ontology

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UnboundLocalError

Python 3.6.8: /usr/bin/python3 Mon May 5 19:30:04 2025

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()

   1471                 pubmed=display_regular_ligand(pdbid,asym_id,lig3,ligIdx,title)

   1472         else:

=> 1473             pubmed,uniprot=display_protein_receptor(pdbid,asym_id,title)

   1474     

   1475     uniprot_line=''

pubmed = '', uniprot = '', display_protein_receptor = <function display_protein_receptor>, pdbid = '7rl5', asym_id = 'Q', title = 'Cryo-EM structures of CTP synthase filaments rev...nsitive assembly during budding yeast starvation.'

 /var/www/html/BioLiP/pdb.cgi in display_protein_receptor(pdbid='7rl5', asym_id='Q', title='Cryo-EM structures of CTP synthase filaments rev...nsitive assembly during budding yeast starvation.')

    840 

    841     if go:

=>  842         display_go(go,uniprot,pdbid,asym_id)

    843     return pubmed,uniprot

    844 

global display_go = <function display_go>, go = '0003883,0006221,0006241', uniprot = '', pdbid = '7rl5', asym_id = 'Q'

 /var/www/html/BioLiP/pdb.cgi in display_go(go='0003883,0006221,0006241', uniprot='', pdbid='7rl5', asym_id='Q')

    481         '''.replace("$namespace_link",namespace_link

    482           ).replace("$namespace",namespace

=>  483           ).replace("$uniprot",u

    484         ))

    485         for l,(term,name) in enumerate(go2aspect[Aspect]):

u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>