Structure of PDB 7rh5 Chain Q

Receptor sequence
>7rh5Q (length=312) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence]
WSDALALGWPTGITPEAKLNRELWIGSVIASFAVGAIVWGLIFWTSAFHR
KKATDTELPRQFGYNMPLELTLTVIPFLIISVLFYFTVVVQERMMHKDPN
PEVVIDVTAFQWNWKFGYQKIAFADGSFDYDGADPERKEAMTSRPEGKDE
HGIEKVGPIRGMTPEDRTYLNFDKIETLGTSSEIPVLVLPAGKRIEFVLN
SADVIHGFWVPEFLFKRDVLPEPKANNSDNVFQVSEIQQTGAFVGRCTEM
CGTFHAMMNFEVRVVEPNDFKAYIDQRNAGKTNAEALAAINQPPLAITTE
PFESRRGELVPQ
3D structure
PDB7rh5 Structure of mycobacterial CIII 2 CIV 2 respiratory supercomplex bound to the tuberculosis drug candidate telacebec (Q203).
ChainQ
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.1.1.9: cytochrome-c oxidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CU Q C273 H281 C247 H255
BS02 CU Q H232 C277 H206 C251
Gene Ontology
Molecular Function
GO:0004129 cytochrome-c oxidase activity
GO:0005507 copper ion binding
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0042773 ATP synthesis coupled electron transport
GO:1902600 proton transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7rh5, PDBe:7rh5, PDBj:7rh5
PDBsum7rh5
PubMed34590581
UniProtA0R057

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