Structure of PDB 7qe7 Chain Q

Receptor sequence

>7qe7Q (length=506) [Search protein sequence]

MNLERLRKRVRQYLDQQQYQSALFWADKVASLSREEPQDIYWLAQCLYLT
AQYHRAAHALRSRKLDKLYEACRYLAARCHYAAKEHQQALDVLDMMSQSS
IKSSICLLRGKIYDALDNRTLATYSYKEALKLDVYCFEAFDLLTSHHMLT
AQEEKELLESLPLSKLCNEEQELLRFLFENKLKKYNKPSETVIPESVDGL
QENLDVVVSLAERHYYNCDFKMCYKLTSVVMEKDPFHASCLPVHIGTLVE
LNKANELFYLSHKLVDLYPSNPVSWFAVGCYYLMVGHKNEHARRYLSKAT
TLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLE
YGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQNGEWKTAEKWFLD
ALEKIKAIGNEVTVDKWEPLLNNLGHVCRKLKKYAEALDYHRQALVLIPQ
NASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLGHCIEMYI
GDSEAY

3D structure

PDB

7qe7 High-resolution structure of the Anaphase-promoting complex (APC/C) bound to co-activator Cdh1

Chain

Resolution

Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	Q	Y212 Y242 Y243 V276 I338 H342 Y373 E377 F403 H406 E407 V410 F413 K443 E445 P446 N449 N450 R456 K457 N478 S480 Y487 L491 F514 M518 M525	Y185 Y215 Y216 V249 I311 H315 Y346 E350 F376 H379 E380 V383 F386 K416 E418 P419 N422 N423 R429 K430 N451 S453 Y460 L464 F487 M491 M498

External links

PDB	RCSB:7qe7, PDBe:7qe7, PDBj:7qe7
PDBsum	7qe7
PubMed

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