Structure of PDB 6y5d Chain Q

Receptor sequence
>6y5dQ (length=94) Species: 9606 (Homo sapiens) [Search protein sequence]
RYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAV
MALQEASEAYLVGLFEDTNLAAIHAKRVTIMPKDIQLARRIRGE
3D structure
PDB6y5d Structural mechanism of cGAS inhibition by the nucleosome.
ChainQ
Resolution4.1 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna Q R41 Y42 V47 K65 L66 R1 Y2 V7 K25 L26
BS02 dna Q Y42 R43 T46 R64 R73 R84 F85 V118 T119 M121 Y2 R3 T6 R24 R33 R44 F45 V78 T79 M81
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:6y5d, PDBe:6y5d, PDBj:6y5d
PDBsum6y5d
PubMed32911482
UniProtQ71DI3|H32_HUMAN Histone H3.2 (Gene Name=H3C15)

[Back to BioLiP]