Structure of PDB 6tps Chain Q

Receptor sequence
>6tpsQ (length=461) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
TFIRGPICGTDNCPSRLWRIIDGRRTCQYGHVMEGDVEFNDDETRRLNLT
TNATGSFQSSQLTNSQLLQQQQRQSHKKFKKLIGHEAKLLFLKSFQFILK
RQIRWLITEMRFPKEFEHVAKIIWLKILKTINDQPQEELKLQLHMTSTIS
ILYLASTHLSLPVYTCDYIKWICTAKMPYFQASEILPKSWRIQLPNYYVS
ILEGSISPFNGQLYNKIALTCGMIHFKEFFNSEISCQGLLLKLVMQCALP
PEFYFYTKQVIEFEETDIRNLTLWERTDERHTGRVSNHAELRVLSYFMLT
INWMLSFDRDRQYPLKWILSLTESLTQRTTTSESIGRNIVKVVYPDKPTS
SDYFQWSEEETLEFLKWMEKQFLPTQTDQKIARRKLYKIFPLDSTHQLTF
IEDLQERYAKQTPFFPPARKEAIGRLLTHIASQLLVDFAISKEQLKDCIS
RIKNACLHRMN
3D structure
PDB6tps Structural basis of RNA polymerase I pre-initiation complex formation and promoter melting.
ChainQ
Resolution3.54 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna Q V212 S213 E216 S218 E292 R504 V199 S200 E203 S205 E279 R451
BS02 dna Q L154 Q155 L156 H157 Y210 Q225 N228 K229 R293 H294 R297 L141 Q142 L143 H144 Y197 Q212 N215 K216 R280 H281 R284
BS03 ZN Q C15 C29 H33 C13 C27 H31
Gene Ontology
Molecular Function
GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0017025 TBP-class protein binding
GO:0046872 metal ion binding
Biological Process
GO:0001188 RNA polymerase I preinitiation complex assembly
GO:0006360 transcription by RNA polymerase I
GO:0042790 nucleolar large rRNA transcription by RNA polymerase I
Cellular Component
GO:0000120 RNA polymerase I transcription regulator complex
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0070860 RNA polymerase I core factor complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6tps, PDBe:6tps, PDBj:6tps
PDBsum6tps
PubMed32139698
UniProtP40992|RRN7_YEAST RNA polymerase I-specific transcription initiation factor RRN7 (Gene Name=RRN7)

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