Structure of PDB 6rwe Chain Q

Receptor sequence
>6rweQ (length=477) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
TFIRGPICGTDNCPSRLWRIIDGRRTCQYGHVMEGDVEFNDDEDLGAGVI
TRRLNLTTNATGSFQSSQLTNSQLLQQQQRQSHKKFKKLIGHEAKLLFLK
SFQFILKRQIRWLITEMRFPKEFEHVAKIIWLKILKTINDQPQEELKLQL
HMTSTISILYLASTHLSLPVYTCDYIKWICTAKMPYFQASEILPKSWRIQ
LPNYYVSILEGSISPFNGQLYNKIALTCGMIHFKEFFNSEISCQGLLLKL
VMQCALPPEFYFYTKQVIEFEETDIRNLTLWERTDERHTGRVSNHAELRV
LSYFMLTINWMLSFDRDRQYPLKWILSLTESLTQRTTTSESIGRNIVKVV
YPDKPTSSDYFQWSEEETLEFLKWMEKQFLPTDQKIARRKLYKIFPLDRE
ANHDGEFNDSTHQLTFIEDLQERYAKQTPFFPPARKEAIGRLLTHIASQL
LVDFAISKEQLKDCISRIKNACLHRMN
3D structure
PDB6rwe Molecular insight into RNA polymerase I promoter recognition and promoter melting.
ChainQ
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna Q D46 K101 L154 Q155 L156 H157 Y210 I214 Q225 K229 R293 H294 D44 K95 L148 Q149 L150 H151 Y204 I208 Q219 K223 R287 H288
BS02 dna Q N209 V212 S213 E216 S218 R293 H294 R504 N203 V206 S207 E210 S212 R287 H288 R467
BS03 ZN Q N14 C29 H33 N12 C27 H31
Gene Ontology
Molecular Function
GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0017025 TBP-class protein binding
GO:0046872 metal ion binding
Biological Process
GO:0001188 RNA polymerase I preinitiation complex assembly
GO:0006360 transcription by RNA polymerase I
GO:0042790 nucleolar large rRNA transcription by RNA polymerase I
Cellular Component
GO:0000120 RNA polymerase I transcription regulator complex
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0070860 RNA polymerase I core factor complex

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Cellular Component
External links
PDB RCSB:6rwe, PDBe:6rwe, PDBj:6rwe
PDBsum6rwe
PubMed31804486
UniProtP40992|RRN7_YEAST RNA polymerase I-specific transcription initiation factor RRN7 (Gene Name=RRN7)

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