Structure of PDB 6q8o Chain Q

Receptor sequence
>6q8oQ (length=353) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
TWSYPVDPYWMVALKALLVVVGLLTAFAFMTLIERRLLARFQVRMGPNRV
GPFGLLQPLADAIKSIFKEDIVVAQADRFLFVLAPLISVVFALLAFGLIP
FGPPGSFFGYQPWVINLDLGILYLFAVSELAVYGIFLSGWASGSKYSLLG
SLRSSASLISYELGLGLALLAPVLLVGSLNLNDIVNWQKEHGWLFLYAFP
AFLVYLIASMAEAARTPFDLPEAEQELVGGYHTEYSSIKWALFQMAEYIH
FITASALIPTLFLGGWTMPVLEVPYLWMFLKIAFFLFFFIWIRATWFRLR
YDQLLRFGWGFLFPLALLWFLVTALVVALDLPRTYLLYLSALSFLVLLGA
VLY
3D structure
PDB6q8o Key role of quinone in the mechanism of respiratory complex I.
ChainQ
Resolution3.605 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HQH Q E225 Q226 E224 Q225
Gene Ontology
Molecular Function
GO:0003954 NADH dehydrogenase activity
GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
GO:0048038 quinone binding
Biological Process
GO:0009060 aerobic respiration
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6q8o, PDBe:6q8o, PDBj:6q8o
PDBsum6q8o
PubMed32811817
UniProtQ60019|NQO8_THET8 NADH-quinone oxidoreductase subunit 8 (Gene Name=nqo8)

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