Structure of PDB 6j6n Chain Q

Receptor sequence
>6j6nQ (length=292) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
DEINEPPPNICEQCLGDEANIRMTKIPQGSECKICTLPFTLYHFKTSKRS
NNIIKTLICVRCATQRNICQCCMLDSRWHIPIQLRDHLISLVNEENVMTE
EAKNDMMKRFLSLKNVKLGGAQITSDPSEADNIVDKLKNILLRAYASVDI
SHILKKLPLNESFLKNPSTKSFFLYNIDASIPEWKITDTVSQLLGIKKWK
DGNSLSLIVNHKAKCGGLRFQSSELGERFVSKISETLVTPKGLKRGVLLI
DRFRIFIIPWSSGFSAASFGTNTAENIKLSLSLNKLIQLELG
3D structure
PDB6j6n Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching.
ChainQ
Resolution3.86 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna Q K47 K50 R51 N53 I55 M108 K45 K48 R49 N51 I53 M106
BS02 rna Q K189 R252 Q254 S295 G296 S298 K156 R219 Q221 S262 G263 S265
BS03 ZN Q C13 C71 C74 C11 C69 C72
BS04 ZN Q C34 C37 C64 C32 C35 C62
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0017070 U6 snRNA binding
GO:0036002 pre-mRNA binding
Biological Process
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0000974 Prp19 complex
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0071006 U2-type catalytic step 1 spliceosome
GO:0071007 U2-type catalytic step 2 spliceosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6j6n, PDBe:6j6n, PDBj:6j6n
PDBsum6j6n
PubMed30879786
UniProtP38241|SLT11_YEAST Pre-mRNA-splicing factor SLT11 (Gene Name=ECM2)

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