Structure of PDB 4v4e Chain Q

Receptor sequence

>4v4eQ (length=875) Species: 35816 (Pelobacter acidigallici) [Search protein sequence]

MGEVVRLTNSSTGGPVFVYVKDGKIIRMTPMDFDDAVDAPSWKIEARGKT
FTPPRKTSIAPYTAGFKSMIYSDLRIPYPMKRKSFDPNGERNPQLRGAGL
SKQDPWSDYERISWDEATDIVVAEINRIKHAYGPSAILSTPSSHHMWGNV
GYRHSTYFRFMNMMGFTYADHNPDSWEGWHWGGMHMWGFSWRLGNPEQYD
LLEDGLKHAEMIVFWSSDPETNSGIYAGFESNIRRQWLKDLGVDFVFIDP
HMNHTARLVADKWFSPKIGTDHALSFAIAYTWLKEDSYDKEYVAANAHGF
EEWADYVLGKTDGTPKTCEWAEEESGVPACEIRALARQWAKKNTYLAAGG
LGGWGGACRASHGIEWARGMIALATMQGMGKPGSNMWSTTQGVPLDYEFY
FPGYAEGGISGDCENSAAGFKFAWRMFDGKTTFPSPSNLNTSAGQHIPRL
KIPECIMGGKFQWSGKGFAGGDISHQLHQYEYPAPGYSKIKMFWKYGGPH
LGTMTATNRYAKMYTHDSLEFVVSQSIWFEGEVPFADIILPACTNFERWD
ISEFANCSGYIPDNYQLCNHRVISLQAKCIEPVGESMSDYEIYRLFAKKL
NIEEMFSEGKDELAWCEQYFNATDMPKYMTWDEFFKKGYFVVPDNPNRKK
TVALRWFAEGREKDTPDWGPRLNNQVCRKGLQTTTGKVEFIATSLKNFEE
QGYIDEHRPSMHTYVPAWESQKHSPLAVKYPLGMLSPHPRFSMHTMGDGK
NSYMNYIKDHRVEVDGYKYWIMRVNSIDAEARGIKNGDLIRAYNDRGSVI
LAAQVTECLQPGTVHSYESCAVYDPLGTAGKSADRGGCINILTPDRYISK
YACGMANNTALVEIEKWDGDKYEIY

3D structure

PDB

4v4e Crystal structure of pyrogallol-phloroglucinol transhydroxylase, an Mo enzyme capable of intermolecular hydroxyl transfer between phenols

Chain

Resolution

2.0 Å

3D
structure

Catalytic site residues are labeled in the structure
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Enzymatic activity

Catalytic site (original residue number in PDB)	Y62 S142 H144 D174 W176 E177 D396 Y404
Catalytic site (residue number reindexed from 1)	Y62 S142 H144 D174 W176 E177 D396 Y404
Enzyme Commision number	1.97.1.2: pyrogallol hydroxytransferase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	CA	Q	W339 A340 K342 Q377	W339 A340 K342 Q377
BS02	MGD	Q	S142 S143 H144 H145 M146 D174 S175 R359 Y496 P499 T503 Q525 I527 D589 S736 H738 H744 T745 M746 E818 N840 M855 N857 N858	S142 S143 H144 H145 M146 D174 S175 R359 Y496 P499 T503 Q525 I527 D589 S736 H738 H744 T745 M746 E818 N840 M855 N857 N858
BS03	MGD	Q	Y62 H144 S175 S216 D218 T221 N222 G224 I225 D249 P250 D271 G350 W354 G355 G356 A357 H362 L735 P737 H738 P739 S742 M743 H744	Y62 H144 S175 S216 D218 T221 N222 G224 I225 D249 P250 D271 G350 W354 G355 G356 A357 H362 L735 P737 H738 P739 S742 M743 H744
BS04	BTT	Q	S143 H144 D174 S175 W176 W354 Y404 C557 Y560	S143 H144 D174 S175 W176 W354 Y404 C557 Y560

Gene Ontology

	Molecular Function
GO:0009055	electron transfer activity
GO:0016491	oxidoreductase activity
GO:0018706	pyrogallol hydroxytransferase activity
GO:0030151	molybdenum ion binding
GO:0043546	molybdopterin cofactor binding
GO:0046872	metal ion binding

	Biological Process
GO:0009061	anaerobic respiration

	Cellular Component
GO:0030288	outer membrane-bounded periplasmic space

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Molecular Function

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Cellular Component

External links

PDB	RCSB:4v4e, PDBe:4v4e, PDBj:4v4e
PDBsum	4v4e
PubMed	15284442
UniProt	P80563\|PGTL_PELAC Pyrogallol hydroxytransferase large subunit (Gene Name=athL)

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