Structure of PDB 4dr6 Chain Q

Receptor sequence

>4dr6Q (length=100) Species: 300852 (Thermus thermophilus HB8)

PKKVLTGVVVSDKMQKTVTVLVERQFPHPLYGKVIKRSKKYLAHDPEEKY
KLGDVVEIIESRPISKRKRFRVLRLVESGRMDLVEKYLIRRQNYQSLSKR

3D structure

• PDB: 4dr6 A structural basis for streptomycin-induced misreading of the genetic code.
• Chain: Q
• Resolution: 3.3 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	Q	P2 K3 S12 K14 M15 Q16 K17 T18 R25 L31 Y32 K34 R38 S39 K40 K41 Y42 E61 S62 R63 P64 I65 S66 K67 R68 K69 R70 R72 R91 N94 Y95 S97 L98 S99 K100	P1 K2 S11 K13 M14 Q15 K16 T17 R24 L30 Y31 K33 R37 S38 K39 K40 Y41 E60 S61 R62 P63 I64 S65 K66 R67 K68 R69 R71 R90 N93 Y94 S96 L97 S98 K99
BS02	MG	Q	M15 E49	M14 E48

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome
• GO:0022627 cytosolic small ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:4dr6, PDBe:4dr6, PDBj:4dr6
• PDBsum: 4dr6
• PubMed: 23322043
• UniProt: P0DOY7|RS17_THET8 Small ribosomal subunit protein uS17 (Gene Name=rpsQ)