Structure of PDB 3wst Chain Q

Receptor sequence
>3wstQ (length=632) Species: 6239 (Caenorhabditis elegans) [Search protein sequence]
MFLEKINQKTGEREWVVAEEDYDMAQELARSRFGDMILDFDRNDKFLAGL
KTTIAEKKHVHVLDIGTGTGLLSLMAAREGADKVTALEVFKPMGDCARHI
TSNSPWSDKITVISERSTDSRADIIVAEVFDTELIGEGALRTFKEALERL
AKPGCRVVPSTGNVYIVPVESHLLKMFNDIPRLNGEKDEEPLGRCSGTAA
VFDVQLSEMKTHEFRELSEPIVAFKFDFEHEEKIIFDESFVREAVAHSSG
TIDALLMWWDIDMDRNGTTFIDMGPKWKNKNNYAWRDHWMQAVYYLPEKK
KVEMNQTFEIVCNHDEFSLWFSNVGKDKSRSYCVCGLHSMLSRQTVYHVN
EMFENQKFKDEVDKLSKGLHVATVGEGSFLGLLAAKTAKRVTIIDGNERF
RDIFFKYIHYYKLTNVEIIEKVTSLTDSPDIVLAEPFYMSAMNPWNHLRF
LYDVEVLKMMHGDELRVEPHMGVLKAIPEKFEDLQNIASDVGTVNGFDLS
FFDEISTKARTATDAIVDEQSLWEYAGIVKGDAVEILRFPIDGRVSSQKC
VVNIDNMSSSNAIPMWMEWEFGGINLSTGLLSISSAGVPEWNKGYKQGVY
FPITALRNDKSLCLHALFDKSTGDINFQFGKS
3D structure
PDB3wst Protein arginine methyltransferase 7 has a novel homodimer-like structure formed by tandem repeats
ChainQ
Resolution2.39 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) E140 E149
Catalytic site (residue number reindexed from 1) E128 E137
Enzyme Commision number 2.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH Q F33 M36 R42 I71 G72 T73 G74 L78 E94 V95 R122 S123 E140 F33 M36 R42 I65 G66 T67 G68 L72 E88 V89 R116 S117 E128
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0016274 protein-arginine N-methyltransferase activity
GO:0042054 histone methyltransferase activity
Biological Process
GO:0006338 chromatin remodeling
GO:0006479 protein methylation
GO:0018216 peptidyl-arginine methylation
GO:0032259 methylation

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Molecular Function
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Biological Process
External links
PDB RCSB:3wst, PDBe:3wst, PDBj:3wst
PDBsum3wst
PubMed24726727
UniProtQ9XW42|ANM7_CAEEL Protein arginine N-methyltransferase 7 (Gene Name=prmt-7)

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