Structure of PDB 8hih Chain P

Receptor sequence
>8hihP (length=213) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
MLELLLLTSELYPDPVLPALSLLPHTVRTAPAEASSLLEAGNADAVLVDA
RNDLSSGRGLCRLLSSTGRSIPVLAVVSEGGLVAVSADWGLDEILLLSTG
PAEIDARLRLVVGLGKVSLGELVIDEGTYTARLRGRPLDLTYKEFELLKY
LAQHAGRVFTRAQLLHEVWGYDFFGGTRTVDVHVRRLRAKLGPEHEALIG
TVRNVGYKAVRPA
3D structure
PDB8hih Structural insights into the transcription activation mechanism of the global regulator GlnR from actinobacteria.
ChainP
Resolution3.66 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna P F184 T187 T189 F174 T177 T179
BS02 dna P R188 R195 R198 T211 R213 N214 R178 R185 R188 T201 R203 N204
Gene Ontology
Molecular Function
GO:0000156 phosphorelay response regulator activity
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
Biological Process
GO:0000160 phosphorelay signal transduction system
GO:0006355 regulation of DNA-templated transcription
GO:0042128 nitrate assimilation
GO:0045893 positive regulation of DNA-templated transcription
Cellular Component
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0032993 protein-DNA complex

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Cellular Component
External links
PDB RCSB:8hih, PDBe:8hih, PDBj:8hih
PDBsum8hih
PubMed37216560
UniProtO53830

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