Structure of PDB 8e7s Chain P

Receptor sequence
>8e7sP (length=236) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
DVPTPYACYFQDSATPNQEGILELHDNIMFYLLVILGLVSWMLYTIVMTY
SKNPIAYKYIKHGQTIEVIWTIFPAVILLIIAFPSFILLYLCDEVISPAM
TIKAIGYQWYWKYEYSDFINDSGETVEFESYVIPDELLEEGQLRLLDTDT
SMVVPVDTHIRFVVTAADVIHDFAIPSLGIKVDATPGRLNQVSALIQREG
VFYGACSELCGTGHANMPIKIEAVSLPKFLEWLNEQ
3D structure
PDB8e7s Structural insights into cardiolipin replacement by phosphatidylglycerol in a cardiolipin-lacking yeast respiratory supercomplex.
ChainP
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.1.1.9: cytochrome-c oxidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEA P P89 L93 P74 L78
BS02 CUA P H186 C225 H229 M232 H171 C210 H214 M217
BS03 CUA P H186 C221 H229 H171 C206 H214
Gene Ontology
Molecular Function
GO:0004129 cytochrome-c oxidase activity
GO:0005507 copper ion binding
GO:0005515 protein binding
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0006123 mitochondrial electron transport, cytochrome c to oxygen
GO:0009060 aerobic respiration
GO:0022900 electron transport chain
GO:0042773 ATP synthesis coupled electron transport
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016020 membrane
GO:0045277 respiratory chain complex IV

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8e7s, PDBe:8e7s, PDBj:8e7s
PDBsum8e7s
PubMed37188665
UniProtP00410|COX2_YEAST Cytochrome c oxidase subunit 2 (Gene Name=COX2)

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