Structure of PDB 7tz6 Chain P

Receptor sequence
>7tz6P (length=378) Species: 9913 (Bos taurus) [Search protein sequence]
TNIRKSHPLMKIVNNAFIDLPAPSNISSWWNFGSLLGICLILQILTGLFL
AMHYTSDTTTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLYMHVGRG
LYYGSYTFLETWNIGVILLLTVMATAFMGYVLPWGQMSFWGATVITNLLS
AIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIIMAIAMVHLLFLH
ETGSNNPTGISSDVDKIPFHPYYTIKDILGALLLILALMLLVLFAPDLLG
DPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAFSILIL
ALIPLLHTSKQRSMMFRPLSQCLFWALVADLLTLTWIGGQPVEHPYITIG
QLASVLYFLLILVLMPTAGTIENKLLKW
3D structure
PDB7tz6 Structure of complex III with bound antimalarial agent CK-2-68 provides insights into selective inhibition of Plasmodium cytochrome bc 1 complexes.
ChainP
Resolution2.88 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM P Q44 G48 R80 H83 G130 L133 H182 F183 P186 Q43 G47 R79 H82 G129 L132 H181 F182 P185
BS02 HEM P W31 G34 L37 H97 V98 R100 S106 W113 G116 H196 L200 N206 W30 G33 L36 H96 V97 R99 S105 W112 G115 H195 L199 N205
BS03 JHB P G142 V145 I146 I268 P270 Y278 G141 V144 I145 I267 P269 Y277
Gene Ontology
Molecular Function
GO:0008121 ubiquinol-cytochrome-c reductase activity
GO:0009055 electron transfer activity
GO:0016491 oxidoreductase activity
GO:0020037 heme binding
GO:0046872 metal ion binding
GO:0048039 ubiquinone binding
Biological Process
GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c
GO:0022904 respiratory electron transport chain
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016020 membrane
GO:0031966 mitochondrial membrane
GO:0045275 respiratory chain complex III

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Cellular Component
External links
PDB RCSB:7tz6, PDBe:7tz6, PDBj:7tz6
PDBsum7tz6
PubMed37236355
UniProtP00157|CYB_BOVIN Cytochrome b (Gene Name=MT-CYB)

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