Structure of PDB 7tr9 Chain P

Receptor sequence
>7tr9P (length=240) Species: 186497 (Pyrococcus furiosus DSM 3638) [Search protein sequence]
MDILLVCLRFPFFSVAKRSYQVRTSFLLPPPSALKGALAKGLILLKPEKY
ASSSLDEAALKAIKEIESKLVDIKAVSVAPLSPLIRNAFLLKRLRNLESG
SNAEKSDAMRREYTFTRELLVAYIFKNLTQEEKNLYLKAAMLIDVIGDTE
SLATPVWASFVKPEDKKAPLAFSAPYTEIYSLRMYIEKMRVSPEYSQEEI
FYLPIEERRYKRIVYYARIYPPEVEKALTVDGEVLGIWIP
3D structure
PDB7tr9 Allosteric control of type I-A CRISPR-Cas3 complexes and establishment as effective nucleic acid detection and human genome editing tools.
ChainP
Resolution3.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna P A16 K17 R18 F26 S32 A33 G36 K40 I43 L55 L90 L91 K92 R93 L94 L97 A108 V145 I146 G147 D148 T149 R201 Y206 A16 K17 R18 F26 S32 A33 G36 K40 I43 L55 L90 L91 K92 R93 L94 L97 A108 V145 I146 G147 D148 T149 R190 Y195
BS02 dna P Y20 R95 K105 D107 Y20 R95 K105 D107
Gene Ontology
Biological Process
GO:0051607 defense response to virus

View graph for
Biological Process
External links
PDB RCSB:7tr9, PDBe:7tr9, PDBj:7tr9
PDBsum7tr9
PubMed35835111
UniProtA0A5C0XNV9

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