Structure of PDB 6p5j Chain P

Receptor sequence

>6p5jP (length=136) Species: 9986 (Oryctolagus cuniculus)

SLGPQVAEGENVFGVCHIFASFNDTFVHVTDLSGKETICRVTGGMKVKAD
RDESSPYAAMLAAQDVAQRCKELGITALHIKLRATGGNRTKTPGPGAQSA
LRALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRL

3D structure

• PDB: 6p5j The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs.
• Chain: P
• Resolution: 3.1 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	P	H32 N38 D39 F41 H43 S48 G49 K50 E51 T52 R55 T57 G59 M60 K63 D65 R66 R98 G102 P134 I135 P136 S137 D138 S139 T140 R141 K143 G144 G145 R146 R147 R149 R150 L151	H17 N23 D24 F26 H28 S33 G34 K35 E36 T37 R40 T42 G44 M45 K48 D50 R51 R83 G87 P119 I120 P121 S122 D123 S124 T125 R126 K128 G129 G130 R131 R132 R134 R135 L136

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0000028 ribosomal small subunit assembly
• GO:0006412 translation

Cellular Component

• GO:0005634 nucleus
• GO:0005730 nucleolus
• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0015935 small ribosomal subunit
• GO:0022627 cytosolic small ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:6p5j, PDBe:6p5j, PDBj:6p5j
• PDBsum: 6p5j
• PubMed: 31609474
• UniProt: G1T1F0|RS14_RABIT Small ribosomal subunit protein uS11 (Gene Name=RPS14)