Structure of PDB 6lqm Chain P

Receptor sequence

>6lqmP (length=50) Species: 9606 (Homo sapiens)

SSHKTFRIKRFLAKKQKQNRPIPQWIRMKTGNKIRYNSKRRHWRRTKLGL

3D structure

• PDB: 6lqm Structural snapshots of human pre-60S ribosomal particles before and after nuclear export.
• Chain: P
• Resolution: 3.09 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	P	S2 S3 H4 K5 K10 L13 Q17 K34 I35 R36 Y37 S39 K40 R41 R42 H43 W44 R45 K48 L49 L51	S1 S2 H3 K4 K9 L12 Q16 K33 I34 R35 Y36 S38 K39 R40 R41 H42 W43 R44 K47 L48 L50
BS02	rna	P	F7 K15 K18 Q19 R21 I23 W26 I27 M29 K30 T31 I35	F6 K14 K17 Q18 R20 I22 W25 I26 M28 K29 T30 I34

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0002227 innate immune response in mucosa
• GO:0006412 translation
• GO:0019731 antibacterial humoral response
• GO:0050830 defense response to Gram-positive bacterium
• GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide

Cellular Component

• GO:0005615 extracellular space
• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:0022626 cytosolic ribosome
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:6lqm, PDBe:6lqm, PDBj:6lqm
• PDBsum: 6lqm
• PubMed: 32669547
• UniProt: P62891|RL39_HUMAN Large ribosomal subunit protein eL39 (Gene Name=RPL39)