Structure of PDB 6j6n Chain P

Receptor sequence
>6j6nP (length=205) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
AILTDQIAKNVKLDDFIPKRQSNFELSVPLPTKAEIQECTARTKSYIQRL
VNAKLANSNNRASSRYVAPANLLLNNSHHIEVVSKQMDPLLPRFVGKKAR
KVVAPTENDEVVPVLHMDGGEADPNEWKIPAAVSNWKNPNGYTVALERRV
ENNTINDGFMKLSEALENADKKARQEIRSKMELKRLAMEQEMLAKESKLK
ELSQR
3D structure
PDB6j6n Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching.
ChainP
Resolution3.86 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna P R92 Y93 R65 Y66
BS02 rna P K117 V127 K133 K85 V95 K101
BS03 rna P N174 P175 N176 Y178 R185 N138 P139 N140 Y142 R149
Gene Ontology
Molecular Function
GO:0000384 first spliceosomal transesterification activity
GO:0000386 second spliceosomal transesterification activity
GO:0005515 protein binding
Biological Process
GO:0000350 generation of catalytic spliceosome for second transesterification step
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0071006 U2-type catalytic step 1 spliceosome
GO:0071007 U2-type catalytic step 2 spliceosome
GO:0071014 post-mRNA release spliceosomal complex

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Cellular Component
External links
PDB RCSB:6j6n, PDBe:6j6n, PDBj:6j6n
PDBsum6j6n
PubMed30879786
UniProtP28004|PRP45_YEAST Pre-mRNA-processing protein 45 (Gene Name=PRP45)

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