Structure of PDB 6hif Chain P

Receptor sequence

>6hifP (length=531) Species: 174633 (Candidatus Kuenenia stuttgartiensis) [Search protein sequence]

VEIITHWVPHEVYGMPGEPDNSGKVFFSGLKAKYMGYPKDAQRSPYPGKY
SKFWKTLPAYRYYIPDYMYNRDEVRPSNPIKGTFKLEQCVACHSVMTPGI
VRDYNKSAHSKAEPAPTGCDTCHGNNHQKLTMPSSKACGTAECHETQYNE
QGQGGIGSHASCSSFAQVECAWSIERPPGDTAGCTFCHTSPEERCSTCHQ
RHQFDPAVARRSEQCKTCHWGKDHRDWEAYDIGLHGTVYQVNKWDTEQFD
FSKKLSDADYVGPTCQYCHMRGGHHNVQRASIVYTSMGMSMADRGAPLWK
EKRDRWVSICDDCHSPRFARENLQAMDESVKDASLKYRETFKVAEDLLID
GVLDPMPKDLCPDWSGQHIWSLKIGAYHDGEAYGGTTGESGEFRMSNCTD
VERLCFESVGYFQTYIYKGMAHGSWNDATYSDGSFGMDRWLVNVKQNASR
ARRLAALEKKVGISWQPEQFWKTGEWLDQLTGPYIVKNHPGKTIFDLCPD
PGWLDTHHAPAEEVEYIERKLKELGITAGSH

3D structure

PDB

6hif A 192-heme electron transfer network in the hydrazine dehydrogenase complex.

Chain

Resolution

2.8 Å

3D
structure

Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Enzymatic activity

Catalytic site (original residue number in PDB)	H220 D255 H256 Y462
Catalytic site (residue number reindexed from 1)	H188 D223 H224 Y430
Enzyme Commision number	1.7.2.8: hydrazine dehydrogenase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	HEC	P	Y94 Y101 P111 I112 F116 C121 C124 H125 C151 H155 G156 H159 L162 M164	Y62 Y69 P79 I80 F84 C89 C92 H93 C119 H123 G124 H127 L130 M132
BS02	HEC	P	Y94 H125 I132 Y136 H141 G150 C151 C154 H155 M164 P165 R226 R233 H234 F236	Y62 H93 I100 Y104 H109 G118 C119 C122 H123 M132 P133 R194 R201 H202 F204
BS03	HEC	P	A140 H141 T149 C170 C175 H176 C227 F236 P238	A108 H109 T117 C138 C143 H144 C195 F204 P206
BS04	HEC	P	H176 Q179 Q183 C227 T229 C230 H231 A241 R242 K286 L287 H307	H144 Q147 Q151 C195 T197 C198 H199 A209 R210 K254 L255 H275
BS05	HEC	P	G189 H191 C194 A198 H220 P223 C247 C250 H251 Q298 H301 V309 Q310 Y316	G157 H159 C162 A166 H188 P191 C215 C218 H219 Q266 H269 V277 Q278 Y284
BS06	HEC	P	H251 Y262 P295 T296 C297 C300 H301 S313 R326 W338 Y449 A453 H454	H219 Y230 P263 T264 C265 C268 H269 S281 R294 W306 Y417 A421 H422
BS07	HEC	P	L266 H267 V293 G294 P295 C342 C345 H346 F350 N354 W457	L234 H235 V261 G262 P263 C310 C313 H314 F318 N322 W425
BS08	HEC	P	A198 Q199 C202 T213 C216 C219 H220 H256 Y316 M319 K450	A166 Q167 C170 T181 C184 C187 H188 H224 Y284 M287 K418
BS09	HEC	P	N458 Y462	N426 Y430
BS10	HEC	P	S347 P348 R349	S315 P316 R317
BS11	HEC	P	H346 S347 F350	H314 S315 F318
BS12	HEC	P	V33 E34 I36	V1 E2 I4
BS13	HEC	P	Y95 R226 S228 Q232 R233	Y63 R194 S196 Q200 R201

External links

PDB	RCSB:6hif, PDBe:6hif, PDBj:6hif
PDBsum	6hif
PubMed	31001586
UniProt	Q1PW30\|HDH_KUEST Hydrazine dehydrogenase (Gene Name=kustc0694)

[Back to BioLiP]