Structure of PDB 6fo2 Chain P

Receptor sequence
>6fo2P (length=370) Species: 9913 (Bos taurus) [Search protein sequence]
LMKIVNNAFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTSDT
TTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLYMHVGRGLYYGSYTF
LETWNIGVILLLTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTN
LVEWIWGGFSVDKATLTRFFAFHFILPFIIMAIAMVHLLFLHETGSNNPT
GISSDVDKIPFHPYYTIKDILGALLLILALMLLVLFAPDLLGDPDNYTPA
NPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAFSILILALIPLLHT
SKQRSMMFRPLSQCLFWALVADLLTLTWIGGQPVEHPYITIGQLASVLYF
LLILVLMPTAGTIENKLLKW
3D structure
PDB6fo2 X-ray and cryo-EM structures of inhibitor-bound cytochromebc1complexes for structure-based drug discovery.
ChainP
Resolution4.4 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H201 S205 K227 D228 E271
Catalytic site (residue number reindexed from 1) H192 S196 K218 D219 E262
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM P Q44 I45 G48 L49 L51 Y55 R80 H83 A84 A127 G130 L133 P134 H182 F183 Q35 I36 G39 L40 L42 Y46 R71 H74 A75 A118 G121 L124 P125 H173 F174
BS02 HEM P W31 G34 L37 H97 R100 S106 W113 G116 L119 H196 L197 S205 N206 W22 G25 L28 H88 R91 S97 W104 G107 L110 H187 L188 S196 N197
Gene Ontology
Molecular Function
GO:0008121 ubiquinol-cytochrome-c reductase activity
GO:0009055 electron transfer activity
GO:0016491 oxidoreductase activity
GO:0020037 heme binding
GO:0046872 metal ion binding
GO:0048039 ubiquinone binding
Biological Process
GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c
GO:0022904 respiratory electron transport chain
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016020 membrane
GO:0031966 mitochondrial membrane
GO:0045275 respiratory chain complex III

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6fo2, PDBe:6fo2, PDBj:6fo2
PDBsum6fo2
PubMed29765610
UniProtP00157|CYB_BOVIN Cytochrome b (Gene Name=MT-CYB)

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